Large bowel and rectal neuroendocrine cancer

Large bowel and rectal neuroendocrine cancers are rare cancers. They start in the neuroendocrine cells Open a glossary item of the large bowel (colon) Open a glossary item or back passage (rectum) Open a glossary item. You might also hear them called neuroendocrine neoplasms (NENs). This means the same as neuroendocrine cancer.

There are 2 key groups of large bowel and rectal neuroendocrine cancer: 

  • neuroendocrine tumours (NETs Open a glossary item
  • neuroendocrine carcinomas (NECs Open a glossary item)

NETs and NECs are very different. So it is important to know which one you have. Talk to your doctor or specialist nurse if you are not sure.

Large bowel and rectal neuroendocrine cancer needs different treatments to other more common types of bowel (colorectal) cancer.

What are large bowel and rectal neuroendocrine cancers?

Large bowel and rectal neuroendocrine cancers are rare cancers. There are different types including neuroendocrine tumours (NETs) and neuroendocrine carcinomas (NECs).

Grades, types and stages of large bowel and rectal neuroendocrine cancers

The grade shows how quickly or slowly your cancer cells are dividing and growing. The stage refers to the size of the cancer, and whether it has spread.

Treatment for large bowel and rectal neuroendocrine cancer

Treatment depends on where the cancer started, its size and whether it has spread. Surgery is the main treatment for large bowel and rectal neuroendocrine cancer.

Last reviewed: 
12 Feb 2025
Next review due: 
12 Feb 2028
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