About neuroendocrine tumours (NETs)

Find out about the neuroendocrine system and what neuroendocrine tumours are.

The neuroendocrine system

The neuroendocrine system is made up of nerves and gland cells. It makes hormones and releases them into the bloodstream.

Neuro means nerve and endocrine refers to the cells of the endocrine system. The endocrine system is a network of glands and organs in the body that make hormones. It is also called the hormone system.

There are neuroendocrine cells in most organs of the body, including the:

  • food pipe (oesophagus)
  • stomach
  • lungs
  • small and large bowel
  • pancreas
  • liver
Diagram showing the parts of the body neuroendocrine tumours most commonly develop in
  • Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours
    JK. Ramage (and others)
    Gut. 2005 Jun;54 Suppl 4:iv1-16

  • An overview of the current diagnosis and recent developments in neuroendocrine tumours of the gastroenteropancreatic tract: the diagnostic approach
    P. Kuiper (and others)
    The Netherlands Journal of Medicine. 2011 Jan;69(1):14-20

  • Cancer Principles and practice of oncology (8th edition)
    VT. De Vita, TS. Lawrence, and SA. Rosenberg
    Lippincott, Williams and Wilkins, 2008

  • The pathologic classification of neuroendocrine tumors: a review of nomenclature, grading, and staging systems
    DS. Klimstra (and others)
    Pancreas. 2010 Aug;39(6):707-12

Last reviewed: 
20 Mar 2014

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