About advanced melanoma

Advanced melanoma means the melanoma has spread from where it started to another part of the body. It is also called stage 4 melanoma.

Your melanoma may have already spread when it was diagnosed. Or it may have come back in another part of the body some time after your first diagnosis and treatment. Doctors call this recurrent cancer.

Cancer that has spread to another part of the body is called secondary cancer or metastases.

Modern treatments may control melanoma for a long time. And in a small number of patients, there are hopes they may be cured, or treatment can have long term control. 

Where melanoma spreads

Melanoma can spread to almost anywhere in the body but the most common places for it to spread are the:

  • lymph nodes
  • lungs
  • liver
  • bones
  • brain
  • tummy (abdomen)
Diagram showing the most common places for melanoma to spread to

How you might feel

Finding out you have advanced melanoma can be a shock. It’s common to feel uncertain and anxious. It's normal to not be able to think about anything else.

Treatment may be able to shrink the melanoma or stop it growing. You will need to talk to your specialist to understand:

  • what your diagnosis means
  • what’s likely to happen
  • what treatments are available
  • how treatment can help you

Even if the melanoma is advanced, it might be months or sometimes years before your doctor can no longer control it.

  • Cancer and its management (7th edition)
    J Tobias and D Hochhauser
    Wiley‐Blackwell, 2015

  • AJCC Cancer Staging Manual (8th edition)
    American Joint Committee on Cancer
    Springer, 2017

  • Melanoma: Assessment and Management
    National Institute for Health and Care Excellence (NICE), 2015

  • Cancer: Principles and Practice of Oncology (10th edition)
    VT DeVita and others
    Lippincott, Williams and Wilkins, 2015

  • The pervasive nature of uncertainty — a qualitative study of patients with advanced cancer and their informal caregivers
    V Shilling and others
    Journal of Cancer Survivorship, 2017. Volume 11, Issue 5, Pages 590 – 603

Last reviewed: 
01 May 2020
Next review due: 
01 May 2023

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