Having internal radiotherapy (brachytherapy) for womb cancer

Internal radiotherapy for womb cancer means giving radiotherapy to the cancer from inside the body. It is also called brachytherapy.

When you might have internal radiotherapy

When you have surgery your surgeon sends what they remove for various tests in a laboratory. These tests help them work out the risk of your cancer coming back.

Internal radiotherapy for intermediate risk and high-intermediate risk cancer

For intermediate risk womb cancer, you may have internal radiotherapy when your cancer is:

  • stage 1A grade 3
  • stage 1B grade 1 to 2
  • stage 2 grade 1

For high-intermediate womb cancer, your doctor may sometimes consider internal radiotherapy instead of external radiotherapy. This is usually when the risk is lower, and lymph nodes that were removed during surgery are clear of cancer.

You may have up to 3 treatments lasting about 20 minutes each.

Internal radiotherapy if you can’t have surgery

If you can’t have surgery or if you’re not fit enough to have surgery, you may have internal radiotherapy:

  • on its own for a low grade cancer
  • after external radiotherapy for a high grade cancer

Depending on your situation, you may have 3 to 6 treatments lasting about 20 minutes each.

How you have internal radiotherapy

You have treatment in the radiotherapy department. Depending on the type of brachytherapy you have, you might stay in hospital to have it or attend as an outpatient. You usually have treatment as an:

  • inpatient if you haven't had a hysterectomy
  • outpatient if you've had a hysterectomy

Treatment as an inpatient

Before treatment

You go into hospital before your brachytherapy. The nurses take you to the theatre to have an anaesthetic. The anaesthetic may be an injection into your spine (epidural) so you are numb below the waist. Or you have a general anaesthetic, which puts you to sleep.

The doctor puts the applicators into the vagina and cervix. The applicators are made up of tubes and, or needles. The doctor places gauze inside the vagina to hold the applicators in place. They also put a tube (catheter) into your bladder.

Once the applicators are in place, you cannot leave the bed and must remain flat. Below is a diagram of how the applicators are placed.

Diagram showing the positon of the applicators for internal radiotherapy

You have a CT and, or MRI scan to check the position of the applicators. Below is a photograph of a CT scanner.

Photo of a CT scanner

The nurses on the ward make sure you are comfortable. You can have pain relief if you need it. You remain on the ward while the treatment team produce a treatment plan. This should be ready within a few hours.

During treatment

Once the plan is ready you come down from the ward to the brachytherapy room. The radiographers connect the applicators to the machine. During the treatment, they leave the room and watch you from outside on a CCTV screen.

After treatment

Afterwards, you might have light sedation for the removal of the applicators and bladder catheter. You can then go back to the ward and can usually go home on the same day.

It is important that another adult takes you home. They should also stay with you for 24 hours afterwards. For 24 hours after a general anaesthetic, you should not:

  • drive a car
  • operate machinery
  • drink alcohol

You should not feel unwell after treatment, but you may notice some:

  • slight bleeding from your vagina
  • mild period like cramps

Treatment as an outpatient

This treatment involves placing a tube inside the vagina. Your doctor takes it out once the treatment is over. You are only radioactive when the treatment machine is switched on. So afterwards you are safe to be around everyone, including children.

A special brachytherapy machine in a purpose built room gives the treatment. You won’t feel the radiotherapy, but the tube can feel uncomfortable.

Before treatment

When you arrive for treatment, the radiographers may ask you to empty your bladder. Your doctor or therapy radiographer examines you to check what size applicator they can use for the treatment. The applicator is a tube which comes in different sizes. They put the tube in your vagina and hold it in place with a clamp. They use a gel to help put the applicator in so it’s as comfortable as possible. It should not be painful.

You then have a CT scan, which takes a short time. Your radiographers wait outside while this happens. Below is a photograph of a CT scanner.

Photo of a CT scanner

Your radiographers remove the applicator after the scan and you are free to go home.

Your radiographers and doctors create your radiotherapy plan. They ensure that the area of the cancer will receive a high dose and surrounding areas receive a low dose. This reduces the side effects you might get during and after treatment. 

You often have your first treatment on the same day but may need a more individualised plan. In this case, you will come back on another day for your first treatment.

During treatment

You usually come back for treatment within a week. You stay in the same position as you were for the CT scan. Your radiographers put in the applicator and connect it to the brachytherapy machine. They then leave the room but can still see you on a CCTV screen during treatment.

After treatment

Your radiographers remove the applicator once treatment has finished. You are then free to go home. The process is the same every time.

You should not feel unwell after treatment, but you may notice some:

  • slight bleeding from your vagina
  • mild period like cramp

Travelling to radiotherapy appointments

You might have to travel a long way each day for your radiotherapy. This depends on where your nearest cancer centre is. This can make you very tired, especially if you have side effects from the treatment.

You can ask the therapy radiographers Open a glossary item for an appointment time to suit you. They will do their best, but some departments might be very busy. Some radiotherapy departments are open from 7 am till 9 pm.

Car parking can be difficult at hospitals. Ask the radiotherapy staff if you are able to get free parking or discounted parking. They may be able to give you tips on free places to park nearby.

Hospital transport may be available if you have no other way to get to the hospital. But it might not always be at convenient times. It is usually for people who struggle to use public transport or have any other illnesses or disabilities. You might need to arrange hospital transport yourself.

Some people are able to claim back a refund for healthcare travel costs. This is based on the type of appointment and whether you claim certain benefits. Ask the radiotherapy staff for more information about this and hospital transport.

Some hospitals have their own drivers and local charities might offer hospital transport. So do ask if any help is available in your area.

Side effects

Radiotherapy can cause different side effects including:

  • diarrhoea
  • bladder problems such as a burning feeling when you pass urine or passing urine more often
  • a sore vagina, and vaginal discharge or bleeding

In the long term, your vagina may become shorter, narrower and less stretchy. To try to prevent this, your radiographer or nurse will give you vaginal dilators to use regularly after your radiotherapy treatment.

  • Endometrial cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up
    A Oaknin and others
    Annals of Oncology, 2022 (available online)

  • British Gynaecological Cancer Society (BGCS) uterine cancer guidelines: recommendations for practice

    J Morrison and others

    European Journal of Obstetrics and Gynecology and Reproductive Biology, March 2022. Volume 270, Pages 50 to 89

  • Cancer of the corpus uteri (2021 update)

    M Koskas and others 

    International Journal of Gynaecology and Obstetrics, 2021. Volume 155, Supplement S1, Pages: 45 to 60

  • Endometrial cancer

    BMJ Best Practice, December 2023

    Accessed April 2024

Last reviewed: 
12 Apr 2024
Next review due: 
12 Apr 2027

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