Graft versus host disease (GvHD) is a possible complication after a bone marrow or stem cell transplant from another person. This is called a donor transplant or an allogeneic transplant. It happens when white blood cells in the donated bone marrow or stem cells attack your own body cells.

Understanding more about how GvHD develops and what the treatment is might help you cope if you develop this complication.

What is graft versus host disease (GvHD)?

GVHD is a possible complication of a bone marrow or stem cell transplant from another person.

GvHD symptoms

The symptoms depend on the type of graft versus host disease (GvHD) you have and which parts of your body it affects.

Types and grades of GvHD

There are different types of GvHD. The doctor assesses the type you have and gives it a grade. Knowing the type and grade helps doctors plan your treatment. 

Diagnosing GvHD

You have further tests and investigations if you have symptoms of GvHD.

Preventing GvHD

You have treatment to reduce your risk of developing GvHD.

Treatment of GvHD

Treatment for graft versus host disease (GvHD) can depend on a number of factors, including what type of GvHD you have and where you have it.

Coping with chronic GvHD

Chronic GvHD can be difficult to cope with. Find out more about how it might affect you and what support is available. 

Resources and support

There are lots of organisations, support groups and helpful books to help you cope with symptoms and side effects caused by cancer and its treatment.

Last reviewed: 
08 Mar 2022
Next review due: 
08 Mar 2025