Not enough fluid in your body (dehydration)

Cancer and some of its treatments can lead to you not having enough fluid in your body (dehydration).

Cause of dehydration

Cancer and some treatments such as chemotherapy, targeted cancer drugs and immunotherapy can cause the following side effects:

  • vomiting

  • diarrhoea

  • sweating because of a fever

  • loss of appetite

You might also lose fluid from your stomach or bowel if you have tubes or drains after surgery.

These side effects, when severe, might stop you from eating and drinking enough. Or cause you to lose more fluid and salts (electrolytes) from your body than you can take in. When this happens, it is called dehydration. 

Symptoms

The symptoms of dehydration can include:

  • feeling thirsty
  • peeing less
  • dark coloured or strong smelling pee
  • feeling very tired
  • dizziness
  • dry mouth, skin and eyes
  • sunken eyes
  • muscle weakness and cramps
  • headaches
  • feeling sick
  • losing weight
  • breathing faster
  • low blood pressure
  • raised body temperature

If you are severely dehydrated you can become confused and very unwell. 

Managing dehydration

You can increase your fluid intake by drinking more. This can be any fluid, not just water. So you can drink tea, squash and juices. Soup and milky drinks also count and can provide some nutrition as well. Try to have 8 to 10 glasses of fluid a day.

Your doctor might suggest drinks that contain salts and electrolytes to replace the lost fluid. They can also give you medicines to help with the cause of your dehydration, such as anti sickness medicines.

You might need fluids through a drip into your bloodstream (intravenously) if you can't drink enough. You may have to stay in hospital for this.

It might be more difficult to correct dehydration if you have advanced cancer.

  • The Royal Marsden Manual of Clinical and Cancer Nursing Procedures (10th edition, online)
    S Lister, J Hofland and H Grafton 
    Wiley Blackwell, 2020

  • Etiology, clinical manifestations, and diagnosis of volume depletion in adults
    UpToDate 
    Accessed September 2023

  • The Eatwell Guide: Helping you eat a healthy, balanced diet
    Public Health England, 2018

  • A multidisciplinary consensus on dehydration: definitions, diagnostic methods and clinical implications
    J Lacey and others
    Annals of Medicine, 2019. Volume 5. Pages 232-251

  • The Nutrition and Hydration Digest (3rd edition)
    The Association of UK Dietitians, 2023

  • Tips to help with eating problems after critical illness
    The Association of UK Dietitians, 2020

Last reviewed: 
14 Sep 2023
Next review due: 
14 Sep 2026

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